What Are CMS' Part B Rebatable Drugs for 2026?

We’ve got the Centers for Medicare & Medicaid Services’ (CMS) most recent list of Medicare Part B drugs your clients may pay reduced coinsurance for from January through March 2026!

CMS publishes the Medicare Part B rebatable drugs quarterly. Keep reading to see the latest Part B rebate guidance.

Inflation-Adjusted Coinsurances for Medicare Part B Drugs

As a reminder, Medicare Part B generally covers drugs provided in doctors’ offices and hospital outpatient departments. Part B drugs may qualify for price adjustments as a result of the Medicare Prescription Drug Inflation Rebate provision in the Inflation Reduction Act (IRA).

The provision states that drug manufacturers who increase the prices of their drugs faster than the rate of inflation must reimburse Medicare for the difference. The reimbursement comes in the form of a rebate, hence the name “Part B rebatable drugs.”

CMS then passes the savings back to Medicare enrollees through inflation-adjusted Part B coinsurances.

Rebatable Part B Drugs with Reduced Coinsurance for 2026

Recently, CMS published their January 2026 ASP Pricing File, noting the 91 Part B prescription drugs that may have lower beneficiary coinsurance rates for January, February, and March due to their prices increasing faster than inflation.

Note: CMS releases information on inflation-adjusted coinsurances via their quarterly Average Sales Price (ASP) public files. Occasionally, CMS updates these after they release them, before the changes go into effect.

Q1 2026 Part B Rebatable Drugs

DrugInflation-Adjusted Coinsurance
Percentage (Normally 20%)
Inj., omadacycline, 1 mg19.631
Inj., eravacycline, 1 mg19.461
Inj velmanase alfa-tycv, 1 mg19.262
Inj, remdesivir, 1 mg18.363
Inj, amiodarone (nexterone)12.189
Inj, rezafungin, 1 mg19.660
Peng benzathine/procaine inj15.234
Penicillin g benzathine inj11.741
Injection, burosumab-twza 1m18.302
C-1 esterase, berinert18.720
Canakinumab injection19.297
Inj ceftolozane tazobactam18.322
Collagenase, clost hist inj17.740
Inj crotalidae im f(ab’)2 eq6.346
Injection, imetelstat, 1 mg19.541
Denosumab injection17.585
Digoxin immune fab (ovine)19.734
Inj, sutimlimab-jome, 10 mg19.974
Inj tofersen intrathetc, 1 mg19.924
Elosulfase alfa, injection19.805
Inj, fosaprepitant (teva)12.833
Galsulfase injection19.781
Hizentra injection19.078
Hyqvia 100 mg immuneglobulin19.994
Inj, panzyga, 500 mg19.150
Hemin, 1 mg18.498
Dalteparin sodium14.304
Ibuprofen injection19.330
Inj, spesolimab-sbzo, 1 mg19.864
Leuprolide acetate /3.75 mg18.309
Inj leu acet lutr dpt 7.5 mg16.261
Inj, meropenem (b. braun)10.069
Inj, mirikizumab-mrkz, 1 mg17.364
Naltrexone, depot form19.997>
Inj ocrelizumab 1 mg hya-ocsq19.659
Palifermin injection16.137
Inj, pasireotide long acting15.093
Pegloticase injection19.008
Inj, romiplostim 1 microgram18.399
Sargramostim injection19.806
Injection, siltuximab17.853
Inj. eptinezumab-jjmr, 1 mg18.798
Inj talquetamab-tgvs 0.25 mg18.982
Inj tedizolid phosphate19.921
Tenecteplase injection17.808
Inj. romosozumab-aqqq, 1 mg18.982
Testosterone undecanoate, 1 mg18.707
Triamcinolone a inj prs-free3.920
Inj., triptorelin xr 3.75 mg19.970
Inj. jivi 1 iu19.507
Inj, ixinity, 1 i.u.18.682
Tacrol envarsus ex rel oral19.372
Lymphocyte immune globulin10.992
Tacrolim granules oral susp9.745
Ensifentrine inh, 3 mg19.960
Inj, aspara, rylaze, 0.1 mg19.350
Inj atezolizumb 5 mg hya-tqjs19.687
Injection, belinostat, 10 mg19.638
Injection, blinatumomab18.451
Brentuximab vedotin inj17.405
Injection, carfilzomib, 1 mg17.981
Inj, amivantamab-vmjw18.787
Inj, elahere, 1 mg19.969
Inj cyclophos frindovyx, 5 mg9.037
Inj daunorubicin, cytarabine19.230
Inj enfort vedo-ejfv 0.25 mg19.550
Inj gemcitabine hcl (accord)18.560
Goserelin acetate implant16.889
Ixabepilone injection19.778
Inj. isatuximab-irfc, 10 mg19.836
Pegaspargase injection18.721
Pentostatin injection19.188
Inj. tagraxofusp-erzs, 10 mcg19.648
Inj, tisotu vedotin-tftv, 1 mg18.580
Inj, tebentafusp-tebn, 1 mcg19.999
Inj pemetrexed (sandoz) 10 mg18.408
Obinutuzumab inj19.492
Panitumumab injection18.287
Injection, pertuzumab, 1 mg19.643
Inj pemetrexed (teva), 10 mg18.896
Inj talimogene laherparepvec18.879
Inj. margetuximab-cmkb, 5 mg19.662
Inj. ado-trastuzumab emt, 1 mg19.994
Inj. fam-trastu deru-nxki, 1 mg19.167
Inj. teclistamab cqyv, 0.5 mg19.323
Axicabtagene ciloleucel car+18.350
Tisagenlecleucel car-pos t18.547
Brexucabtagene car pos t19.952
Lisocabtagene mara car pos t18.308
Idecabtagene vicleucel car18.857
Ciltacabtagene car-pos t18.291

Source: CMS.gov

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For more info on the Medicare Prescription Drug Rebate Program, visit CMS.gov/inflation-reduction-act-and-medicare/inflation-rebates-medicare.

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